Degeneration and Regeneration of Subbasal Corneal Nerves after Infectious Keratitis

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Degeneration and Regeneration of Subbasal Corneal Nerves after Infectious Keratitis

Purpose—To investigate the longitudinal alterations of subbasal corneal nerves in patients with infectious keratitis (IK) during acute phase, cessation of treatment and recovery phase by in vivo confocal microscopy (IVCM). Design—Prospective, longitudinal, case-control, single-center study. Subjects—Fifty-six eyes of 56 patients with the diagnosis of bacterial (n=28), fungal (n=15), and Acantha...

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Degeneration and Regeneration of Subbasal Corneal Nerves after Infectious Keratitis: A Longitudinal In Vivo Confocal Microscopy Study.

PURPOSE To investigate the longitudinal alterations of subbasal corneal nerves in patients with infectious keratitis (IK) during the acute phase, cessation of treatment, and the recovery phase by in vivo confocal microscopy (IVCM). DESIGN Prospective, longitudinal, case-control, single-center study. PARTICIPANTS Fifty-six eyes of 56 patients with the diagnosis of bacterial (n=28), fungal (n...

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Degeneration and regeneration of corneal nerves.

CERTAIN authors, such as Haab (1899), Kraupa (1924), and Walsh (1947), have suggested that there might be an inter-relation between certain diseases of the cornea and the condition of the corneal nerves. The diseases mentioned are recurrent erosion of the cornea, superficial punctate keratitis, herpetic keratitis, and certain forms of degeneration of the corneal epithelium. Neuroparalytic kerat...

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corneal epithelial dendritic cells and subbasal corneal nerve plexus in herpes simplex keratitis versus acanthamoeba keratitis

purpose: to investigate confocal scan features of corneal subbasal nerve plexus and epithelial dendritic cells in herpes simplex keratitis (hsk) as compared to acanthamoeba keratitis (ak). methods: confocal scan records of patients with clinical and confocal microscopic features compatible with hsk and ak as well as confocal scan records of normal participants were reviewed. the density and mor...

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The desert hedgehog (Dhh) signaling pathway is involved in the development of peripheral nerves (PNs). Dhh-null mice show abnormal neuronal development and perineurial barrier function. As it was previously shown that dhh is mainly expressed in developmental nerves and Sonic hedgehog protein (dhh homologous) has therapeutic effects in neuronal survival, we attempted to investigate the possible ...

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ژورنال

عنوان ژورنال: Ophthalmology

سال: 2015

ISSN: 0161-6420

DOI: 10.1016/j.ophtha.2015.06.047